Poggio San Vicino is a commune in Macerata province in the Italian region of  Le Marche region. Wines can be made under the Verdicchio dei Castelli di Jesi Classico DOC and Verdicchio dei Castelli di Jesi Classico DOC Superiore denominations. Poggio San Vicino is located about 28 miles (45 kms) southwest of Ancona and about 18.6 miles (30 kms) northwest of Macerata. As of 31 December 2004, it had a population of 299 and an area of 5 square miles (12.9 square kms).